Our body contains two types of cannabinoid receptors—CB1 and CB2. CB1 receptors are found in the nervous system and brain, while CB2 receptors are located in the immune system and other areas of the body.
CBG works by binding to both receptors where it’s thought to strengthen the function of anandamide, a neurotransmitter that plays a role in enhancing pleasure and motivation, regulating appetite and sleep, and alleviating pain. Unlike THC, CBG has no psychotropic effects, so it will not give you a high.
Research has shown that CBGA can influence 5HT1A-receptors. This receptor is responsible for regulating serotonin levels. CBG can be a moderate block of the receptor, which can affect the serotonin signaling in the central nervous system.
In addition, CBG has been shown to be an adrenoceptor agonist. This helps it control the expression of noradrenaline and adrenaline in the central nervous system. Adrenaline and noradrenaline are major neurotransmitters in the sympathetic nervous system (SNS).